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GKT136901
CAS No. : 955272-06-7
Biological Activity:GKT136901 is a potent, selective and orally active inhibitor of NADPH oxidase (NOX1/4), with Kis of 160 and 165 nM, respectively. GKT136901 is also a selective and direct scavenger of peroxynitrite. GKT136901 can be used for the research of diabetic nephropathy, stroke, and neurodegeneration. GKT136901 also has anti-inflammatory activity[2][3].
Research Area:Metabolic Disease|Inflammation/Immunology|Neurological Disease
Targets:NADPH Oxidase
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Anti-diabetic Compound Library;Oxygen Sensing Compound Library;Ferroptosis Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Human Metabolite Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:VAS2870;APX-115 free base;VAS 3947;NoxA1ds;Diphenyleneiodonium chloride;GSK2795039;Setanaxib;Mulberrofuran G;Fulvene-5;Fluoflavine;GLX351322;ML171
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