P-gp/BCRP-IN-1

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P-gp/BCRP-IN-1

CAS No. : 2764596-06-5

Biological Activity:P-gp/BCRP-IN-1 (compound 19) is a potential, relatively safe, orally active and efficient efflux transporter (P-gp and BCRP) inhibitor. P-gp/BCRP-IN-1 exerts resistance reversal by inhibiting the efflux function of P-gp and BCRP. P-gp/BCRP-IN-1 can overcome the resistance and improve the oral bioavailability of PTX (Paclitaxel).

Research Area:Cancer

Targets:BCRP

Related Small Molecules:PCI 29732;Triclabendazole sulfoxide;Elacridar;YHO-13351;CP-100356 hydrochloride;PD166326;Fumitremorgin C;UR-MB108;Zamicastat;Ko 143;KS176;ML753286;ML230;Triclabendazole sulfoxide-d3;Ac32Az19;6,8-Diprenylnaringenin;FD 12-9;Triclabendazole sulfoxide-13C,d3;YHO-13177

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