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Fosmanogepix
CAS No. : 2091769-17-2
Biological Activity：Fosmanogepix (APX001) is a first-in-class and orally available broad-spectrum antifungal agent, which targets the highly conserved Gwt1 fungal enzyme. Fosmanogepix (APX001) is an N-phosphonooxymethyl prodrug which is rapidly and completely metabolized by systemic alkaline phosphatases to the active moiety, APX001A. Fosmanogepix (APX001) can be used in development for the treatment of invasive fungal infections[2].
Research Area：Infection
Targets：Fungal
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Antifungal Compound Library;
Related Small Molecules:Antifungal agent 20;Debneyol;Haloprogin;Staurosporine;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;(R)-Camptothecin-d5;Ticlatone;Aminothiazole;Magnesium silicate;α-Terpinene;Hydroxyphenyllactic acid;Iprobenfos;Chlorphenesin;Moniliformin sodium salt;HLF1-11;β-Amyrin acetate;Bifonazole;Aszonapyrone A;Oenothein B;Pyrimorph;(+)-Magnoflorine iodide;Antifungal agent 39
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