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ML334
CAS No. : 1432500-66-7
Biological Activity：ML334 is a potent, cell permeable activator of NRF2 by inhibition of Keap1-NRF2 protein-protein interaction. ML334 binds to Keap1 Kelch domain with a Kd of 1 μM. ML334 stimulates NRF2 expression and nuclear translocation and induces antioxidant response elements (ARE) activity[2].
Research Area：Cancer
Targets：Keap1-Nrf2
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