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BMX-IN-1

CAS No. : 1431525-23-3

Biological Activity：BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys⁴⁹⁶ in the BMX ATP binding domain with an IC₅₀ of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC₅₀ value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.

Research Area：Cancer

Targets：BMX Kinase|Btk

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;Chemical Probe Library;Anti-Blood Cancer Compound Library;Targeted Diversity Library;

Related Small Molecules:JAK3/BTK-IN-1;Elsubrutinib;ARQ 531;PF-06250112;PCI 29732;CHMFL-EGFR-202;Avitinib;RN486;GDC-0834 Racemate;Spebrutinib besylate;Vecabrutinib;Tolebrutinib;BTK-IN-16;(R)-Zanubrutinib;Pirtobrutinib;CTA056;EGFR-IN-40;QL-X-138;ACP-5862;BTK-IN-12;JAK3/BTK-IN-4;JAK3/BTK-IN-6;BTK inhibitor 20;SJF620

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