GNF-5

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GNF-5

CAS No. : 778277-15-9

Biological Activity:GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 µM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer[2].

Research Area:Cancer

Targets:Bcr-Abl

Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Chemical Probe Library;Anti-Alzheimer’s Disease Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;

Related Small Molecules:AT9283;Bafetinib;Pivanex;SNIPER(ABL)-039;Flumatinib mesylate;IHMT-TRK-284;SNIPER(ABL)-049;Olverembatinib;GNF-2;CT-721;SNIPER(ABL)-015;BCR-ABL-IN-4;SNIPER(ABL)-033;CHMFL-ABL-039;BCR-ABL-IN-6;c-ABL-IN-2;SNIPER(ABL)-058;ON 146040;HG-7-85-01;CHMFL-ABL/KIT-155;Radotinib-d6;BCR-ABL-IN-1;SIAIS178

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