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Calhex 231 hydrochloride
CAS No. : 2387505-78-2
Biological Activity:Calhex 231 hydrochloride is a CaSR inhibitor via negative allosteric modulation. Calhex 231 hydrochloride blocks Ca2+-induced accumulation of [3H]inositol phosphate with an IC50 of 0.39 μM in HEK293 cells. Calhex 231 hydrochloride has the potential for diabetic cardiomyopathy (DCM) treatment[2].
Research Area:Metabolic Disease
Targets:CaSR
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Anti-diabetic Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:Calcium-Sensing Receptor Antagonists I;SB-423562;Ligustroflavone;NPS 2390;AC-265347;GSK3004774;Etelcalcetide hydrochloride;Gadolinium chloride;Upacicalcet;Strontium Ranelate;NPS-2143;γ-L-Glutamyl-L-alanine;SB-423557;Tecalcet Hydrochloride;Evocalcet
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