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5J-4
CAS No. : 827001-82-1
Biological Activity：5J-4 is a potent CRAC inhibitor. 5J-4 decreases the numbers of infiltrated mononuclear cell into the CNS, and significantly decreases the population of infiltrated CD4+ population. 5J-4 reduces the symptoms and delayed the onset of EAE (experimental autoimmune encephalomyelitis) in mouse model of inflammation.
Research Area：Inflammation/Immunology
Targets：CRAC Channel
Related Small Molecules:RO2959 monohydrochloride;SKF-96365 hydrochloride;GSK-5498A;CRAC intermediate 1;piCRAC-1;MRS1845;Zegocractin;SOCE inhibitor 1;Synta66;CRAC intermediate 2;YM-58483;Tanshinone IIA sulfonate sodium
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