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CHIKV-IN-2

CAS No. : 2361289-44-1

Biological Activity：CHIKV-IN-2 is a potent inhibitor against Chikungunya virus (CHIKV), with excellent cellular antiviral activity (EC₉₀=270 nM) and improved liver microsomal stability. CHIKV-IN-2 shows inhibitory activity against a cellular target Dihydroorotate Dehydrogenase (DHODH), which interacts with various viruses and regulate their replication via depleting intracellular pyrimidine pools.

Research Area：Infection

Targets：Dihydroorotate Dehydrogenase

Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;Ferroptosis Compound Library;Mitochondria-Targeted Compound Library;Targeted Diversity Library;

Related Small Molecules:P1788;PfDHODH-IN-2;PTC299;DHODH-IN-1;Tenovin-6;(E/Z)-Teriflunomide;hDHODH-IN-3;DHODH-IN-4;BAY-2402234;Indoluidin E;DHODH-IN-17;DHODH-IN-15;DHODH-IN-22;hDHODH-IN-7;Brequinar;DSM705 hydrochloride;AG-636;DHODH-IN-11;DSM502;DHODH-IN-19;Farudodstat;hDHODH-IN-4;DHODH-IN-21;Laflunimus;Vidofludimus;ML390;DHODH-IN-13;DSM265

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