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Fluphenazine dimaleate

CAS No. : 3093-66-1

Biological Activity：Fluphenazine dimaleate is a potent, orally active phenothiazine-based dopamine receptor antagonist. Fluphenazine dimaleate blocks neuronal voltage-gated sodium channels. Fluphenazine dimaleate acts primarily through antagonism of postsynaptic dopamine-2 receptors in mesolimbic, nigrostriatal, and tuberoinfundibular neural pathways. Fluphenazine dimaleate can antagonize Methylphenidate-induced stereotyped gnawing and inhibit climbing behaviour in mice. Fluphenazine dimaleate can be used for researching psychosis and painful peripheral neuropathy associated with diabetes and has potential to inhibit SARS-CoV-2^[2]^[3]^[4]^[6].

Research Area：Infection|Neurological Disease

Targets：Dopamine Receptor|Sodium Channel|SARS-CoV

Related Small Molecules:Alizapride hydrochloride;Thioproperazine;Lu AE98134;Bromopride-d3;Zandatrigine;Nuciferine;Glaucine;Veratridine;SARS-CoV-2-IN-33;SB-277011 dihydrochloride;Brompheniramine-d6 maleate;GRL-0496;GX-674;Grazoprevir potassium salt;Dibucaine;MIF-1 TFA;SARS-CoV-2-IN-19;Molnupiravir

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