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EG00229
CAS No. : 1210945-69-9
Biological Activity：EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2.
Research Area：Cancer
Targets：Complement System
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Peptidomimetic Library;Protein-protein Interaction Inhibitor Library;
Related Small Molecules:Cemdisiran;Pelecopan;PMX 205;Factor B-IN-2;Tesidolumab;Factor B-IN-3;Avacincaptad pegol;Sutimlimab;FD-IN-1;NDT 9513727;Cyclosporin A;AMY-101;Lipoteichoic acid;Iptacopan;Entadamide-A-β-D-glucopyranoside;Compstatin TFA;C5aR-IN-2;BCX 1470;EG01377;TLQP-21;W-54011;Complement C5-IN-1;PMX-53;(Z)-Leukadherin-1
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