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Maprotiline hydrochloride

CAS No. : 10347-81-6

Biological Activity：Maprotiline hydrochloride is a selective noradrenalin re-uptake inhibitor and a tetracyclic antidepressant.
Target: Others
Maprotiline (sold as Deprilept, Ludiomil, Psymion) is a tetracyclic antidepressant (TeCA). However, Maprotiline’s fourth ring is spurious, as formed by a bridge across the central tricyclic ring. It is a strong norepinephrine reuptake inhibitor with only weak effects on serotonin and dopamine reuptake. It exerts strong blocking effect at H1 receptors, moderate at 5-HT2 and alpha1 and weak blocking effect at D2 and mACh postsynaptic receptors [1, 2].

Research Area：Neurological Disease

Targets：Autophagy

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Related Small Molecules:Physalin A;Stauprimide;Pregnenolone monosulfate sodium;Notoginsenoside Fc;AGN 193109-d7;AT9283;Ciclopirox-d11;BIX-01294;Wogonoside;Cyclovirobuxine D;Clotrimazole-d5;Curcumin;Loperamide-d6 N-Oxide;Physalin B;Colistin sulfate;Salvianolic acid B;10074-G5;Dehydrocorydaline;Glucosamine-13C hydrochloride

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