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Hycanthone
CAS No. : 3105-97-3
Biological Activity：Hycanthone is a thioxanthenone DNA intercalator and inhibits RNA synthesis as well as the DNA topoisomerases I and II. Hycanthone inhibits nucleic acid biosynthesis and inhibits apurinic endonuclease-1 (APE1) by direct protein binding with a KD of 10 nM. Hycanthone is a bioactive metabolite of Lucanthone (HY-B2098) and has anti-schistosomal agent.
Research Area：Infection
Targets：Parasite|Topoisomerase|DNA/RNA Synthesis
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