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Fenbufen-d9

CAS No. : 1189940-96-2

Biological Activity：Fenbufen-d9 (CL-82204-d9) is the deuterium labeled Fenbufen. Fenbufen (CL-82204) is an orally active non-steroidal anti-inflammatory drug (NSAID), with antipyretic effects. Fenbufen has potent activity in a variety of animal model, including carageenin edema, UV erythema and adjuvant arthritis. Fenbufen has inhibitory activities against COX-1 and COX-2 with IC₅₀s of 3.9 μM and 8.1 μM, respectively. Fenbufen is a caspases (caspase-1, 3, 4, 5, 9) inhibitor^[2]^[3]^[4]^[5].

Research Area：Inflammation/Immunology

Targets：Caspase|COX

Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Dehydrocorydaline;Ampyrone;COX-2-IN-24;Zaltoprofen-d7;Z-DEVD-AMC;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Asaraldehyde;(-)-Epicatechin;20(S)-Ginsenoside Rg3;Ginsenoside Rd;p-nitro-Pifithrin-α;Nimesulide D5;COX-2/5-LOX-IN-1;ML132;S-(+)-Marmesin;Tazofelone;L67;Catechin-13C3;AKN-028 acetate;Diclofenac-d4;Proglumetacin;Ethoxycoronarin D;Ossirene;Phenidone

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