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M1145

CAS No. : 1172089-00-7

Biological Activity：M1145, a chimeric peptide, is a selective galanin receptor type 2 (GAL2) agonist, with a K_i of 6.55 nM. M1145 shows more than 90-fold higher affinity for GAL2 over GAL1 (K_i=587 nM) and a 76-fold higher affinity over GalR3 (K_i=497 nM). M1145 has an additive effect on the signal transduction of galanin.

Research Area：Neurological Disease

Targets：Neuropeptide Y Receptor

Related Small Molecules:[D-Trp34]-Neuropeptide Y TFA;Pancreatic Polypeptide, human;Peptide YY (PYY), human;JNJ-5207787;[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA;GR231118 TFA;Neuropeptide Y (human);RF9 hydrochloride;Galanin Receptor Ligand M35 TFA;Neuropeptide Y (3-36) (porcine);BMS-193885;CART (55-76), rat;Galantide;RFRP-3(human) TFA;BIBO3304 TFA;Neuropeptide SF(mouse,rat);Galanin (1-16), mouse, porcine, rat;FR252384;Galnon;[cPP1-7,NPY19-23,Ala31,Aib32,Gln34]-hPancreatic Polypeptide;CART (1-39), Human, Rat;Neuropeptide Y (13-36), amide, human;Neuropeptide S(Rat);Neuropeptide Y (22-36);Lu AA33810;Neuropeptide Y (3-36) (human, rat)

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