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NCT-501 hydrochloride

CAS No. : 2080306-22-3

Biological Activity：NCT-501 hydrochloride is a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1A1 (ALDH1A1), inhibits hALDH1A1 with IC₅₀ of 40 nM, typically shows better selectivity over other ALDH isozymes and other dehydrogenases (hALDH1B1, hALDH3A1, and hALDH2, IC₅₀ >57 μM)^[2].

Research Area：Cancer

Targets：Aldehyde Dehydrogenase (ALDH)

Related Small Molecules:Alda-1;ALDH3A1-IN-2;ALDH1A3-IN-2;CM10;EN40;Prunetin;ALDH1A1-IN-3;Taraxerone;Win 18446;RV01;KS100;CM037;IGUANA-1 free base;4-Diethylaminobenzaldehyde;CVT-10216;KS106;α-NETA;ALDH1A2-IN-1;CM121;ALDH1A3-IN-1;3-Hydroxybenzaldehyde;ALDH3A1-IN-1;NCT-505;4-Hydroxynonenal-d3;NCT-506;ALDH1A3-IN-3;Dyclonine hydrochloride

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