For research use only. We do not sell to patients.

Mozavaptan hydrochloride

CAS No. : 138470-70-9

Biological Activity：Mozavaptan hydrochloride (OPC-31260 hydrochloride) is a benzazepine derivative and a potent, selective, competitive and orally active vasopressin V₂ receptor antagonist with an IC₅₀ of 14 nM. Mozavaptan hydrochloride shows ~85-fold selectivity for V₂ receptor over V₁ receptor (IC₅₀ of 1.2 μM), and can antagonize the antidiuretic action of arginine vasopressin (AVP) in vivo. Mozavaptan hydrochloride has the potential for hyponatremia, syndrome of inappropriate antidiuretic hormone (SIADH), and congestive heart failure treatment^[2].

Research Area：Cancer|Endocrinology|Metabolic Disease

Targets：Vasopressin Receptor

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus; GPCR/G Protein Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Targeted Diversity Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;

Related Small Molecules:Lixivaptan;Balovaptan;Big Endothelin-1 (1-38), human;WAY-151932;Felypressin;Antagonist G TFA;Mozavaptan-d6;SKF 100398;Fedovapagon;L-371,257;Argipressin;D[LEU4,LYS8]-VP;d[Cha4]-AVP;RG7713;TASP0390325;Terlipressin-d5;SRX246;Terlipressin acetate;SR 49059;Big Endothelin-1 (1-39), porcine

Trending products：Recombinant Proteins  |  Bioactive Screening Libraries  |  Natural Products  |  Fluorescent Dye  |  PROTAC  |  Isotope-Labeled Compounds  |  Oligonucleotides

About Us:

• MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
• Structurally and synthetically diverse biologically active compounds；
•  roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
• We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
• Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

• Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.