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YS-49
CAS No. : 132836-42-1
Biological Activity：YS-49 is a PI3K/Akt (a downstream target of RhoA) activator, to reduce RhoA/PTEN activation in the 3-methylcholanthrene-treated cells. YS-49 inhibits angiotensin II (Ang II)-stimulated proliferation of VSMCs via induction of heme oxygenase (HO)-1. YS-49 is also an isoquinoline compound alkaloid, has a strong positive inotropic action through activation of cardiac β-adrenoceptors[2][3].
Research Area：Cardiovascular Disease|Endocrinology
Targets：Akt|Adrenergic Receptor|Angiotensin Receptor|PI3K
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Kinase Inhibitor Library;Neuronal Signaling Compound Library;PI3K/Akt/mTOR Compound Library; Stem Cell Signaling Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Anti-Cardiovascular Disease Compound Library;Endocrinology Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Neurotransmitter Receptor Compound Library;Glutamine Metabolism Compound Library;Neuroprotective Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Umbralisib hydrochloride;Todralazine;Topoisomerase I/II inhibitor 3;ARC 239 dihydrochloride;Cyclovirobuxine D;Yohimbine;Rigosertib sodium;Tenalisib R Enantiomer;Glaucine;AKTide-2T;Salbutamol;PI3kδ inhibitor 1;BI-167107;Sennidin A;PI3K/VEGFR2-IN-1;Saralasin;Talibegron hydrochloride;MS98;PP2A Cancerous-IN-1;Arotinolol
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