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A-770041
CAS No. : 869748-10-7
Biological Activity：A-770041 is a selective and orally active Src-family Lck inhibitor. A-770041 inhibits Lck with an IC50 value of 147 nM with the presence of 1 mM ATP. A-770041 shows 300-fold selective to Lck over Fyn, the other Src family kinase involved in T-cell signaling. A-770041 can be used for the research of acute rejection[2].
Research Area：Inflammation/Immunology
Targets：Src
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Reprogramming Compound Library;Orally Active Compound Library;Chemical Probe Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;
Related Small Molecules:KB SRC 4;Tirbanibulin dihydrochloride;Bafetinib;p60c-src substrate II;Caffeic acid-pYEEIE TFA;PP2;PP58;ENMD-2076 Tartrate;CH6953755;Fenlean;TL02-59;PF 477736;PD166326;Masitinib;Lyn peptide inhibitor TFA;SM1-71;β-Hydroxyisovalerylshikonin;HG-7-85-01;Squarunkin A hydrochloride;1-NM-PP1;MNS;TG 100801;Scutellarein;TG 100572;AMG-47a
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