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E7449
CAS No. : 1140964-99-3
Biological Activity：E7449 is a potent PARP1 and PARP2 inhibitor and also inhibits TNKS1 and TNKS2, with IC50s of 2.0, 1.0, ∼50 and ∼50 nM for PARP1, PARP2, TNKS1 and TNKS2, respectively, using 32P-NAD+ as substrate.
Research Area：Cancer
Targets：PARP
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Anti-COVID-19 Compound Library;Anti-Breast Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Targeted Diversity Library;
Related Small Molecules:Rucaparib monocamsylate;AZD-2461;Senaparib;Dehydrocorydaline;Rucaparib hydrochloride;Niraparib tosylate;G007-LK;PROTAC PARP1 degrader;UPF 1069;DP-C-4;Δ5-Avenasterol-d4;PARP14 inhibitor H10;CEP-9722;PARP1-IN-11;PI-1840;5,7-Dihydroxychromone;PARP-1/2-IN-1;(8R,9S)-Talazoparib;3-Aminobenzamide;PARP1-IN-12;PARP-1-IN-2;BRCA1-IN-1;NMS-P118;VPC-70063;G244-LM
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