5,7-Dihydroxychromone

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5,7-Dihydroxychromone

CAS No. : 31721-94-5

Biological Activity:5,7-Dihydroxychromone, the extract of Cudrania tricuspidata, activates Nrf2/ARE signal and exerts neuroprotective effects against 6-hydroxydopamine (6-OHDA)-induced oxidative stress and apoptosis. 5,7-Dihydroxychromone inhibits the expression of activated caspase-3 and caspase-9 and cleaved PARP in 6-OHDA-induced SH-SY5Y cells.

Research Area:Neurological Disease

Targets:PARP|Arenavirus|Keap1-Nrf2|Caspase

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