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SAE-14
CAS No. : 1241280-25-0
Biological Activity：SAE-14 (compound SAE-14) is a potent, specific GPR183 antagonist with an IC50 value of 28.5 nM, can antagonize 7α, 25-OHC–induced calcium mobilization with IC50 value below 50 nM in HL-60 cells. GPR183 antagonist-1 can reverse allodynia in mice.
Research Area：Inflammation/Immunology|Neurological Disease
Targets：EBI2/GPR183
Related Screening Libraries:Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Antiviral Compound Library;
Related Small Molecules:GSK682753A;NIBR189;7α,25-Dihydroxycholesterol-d6;7α,25-Dihydroxycholesterol;ML401
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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