Imatinib-d3 hydrochloride

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Imatinib-d3 hydrochloride

CAS No. : 1134803-18-1

Biological Activity:Imatinib-d3 (STI571-d3) hydrochloride is the deuterium labeled Imatinib. Imatinib (STI571) is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR/ABL, v-Abl, PDGFR and c-kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self-inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS-CoV and MERS-CoV.

Research Area:Cancer

Targets:Autophagy|Bcr-Abl|c-Kit|PDGFR|SARS-CoV

Related Small Molecules:AT9283;Bafetinib;Pivanex;Henatinib;SARS-CoV-2-IN-33;GRL-0496;SNIPER(ABL)-039;c-Kit-IN-5-1;Flumatinib mesylate;IHMT-TRK-284;Grazoprevir potassium salt;PDGFRα/FLT3-ITD-IN-2;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;PP58;Chiauranib;SARS-CoV-2-IN-16;Zeteletinib

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