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Elubrixin
CAS No. : 688763-64-6
Biological Activity:Elubrixin (SB-656933) is a potent, selective, competitive, reversible and orally active CXCR2 antagonist and an IL-8 receptor antagonist. Elubrixin inhibits neutrophil CD11b upregulation (IC50 of 260.7 nM) and shape change (IC50 of 310.5 nM). Elubrixin has the potential for inflammatory diseases research, such as inflammatory bowel disease and airway inflammation[2][3].
Research Area:Inflammation/Immunology
Targets:CXCR|Interleukin Related
Related Small Molecules:Nicotinamide N-oxide;AX-024;Ginsenoside F3;Perakizumab;FC131;PNRI-299;CXCR4 antagonist 2;AMG 487 (S-enantiomer);CTX-471;Ac-YVAD-CHO;CXCR4 antagonist 6;Deucravacitinib;CXCR2 antagonist 4;VUF11207 fumarate;Mulberroside A;NFAT Transcription Factor Regulator-1;IL-17A antagonist 1;Kansuinine B;Ginsenoside Rc;KRH-3955 hydrochloride;5(S)15(S)-DiHETE;IL-17A inhibitor 2;Anti-Mouse IL-1b Antibody;IT1t dihydrochloride;Raleukin;Ossirene;VGX-1027;RCGD423;Clazakizumab
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