L-Canaline

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L-Canaline

CAS No. : 496-93-5

Biological Activity:L-Canaline is a nonprotein amino acid stored in many leguminous plants. L-Canaline is a cytotoxic metabolite catalyzed by L-canavanine and its arginase. L-Canaline is a potent and irreversible inhibitor of ornithine aminotransferase. L-Canaline inhibits the growth of the malaria parasite Plasmodium falciparum with an IC50 of 297 nM. L-Canaline has anticancer and antiproliferative effects[2][3].

Research Area:Cancer|Infection

Targets:Parasite|Endogenous Metabolite

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