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gamma-secretase modulator 5
CAS No. : 1353570-53-2
Biological Activity:gamma-secretase modulator 5 (compound 22d) is a brain-penetrant gamma-secretase modulator (GSMs) that inhibits the production of the aggregated amyloid β-peptide Aβ42 with an IC50 value of 60 nM. gamma-secretase modulator 5 can be used in the study of Alzheimer’s disease.
Research Area:Neurological Disease
Targets:Amyloid-β
Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;β-Amyloid (11-22);20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Aβ-IN-1;Qingyangshengenin B;JNJ-40418677;HDAC6-IN-6;β-Amyloid (1-37) (human);CGP52411;Astrophloxine;γ-Secretase modulator 12;δ-Secretase inhibitor 11;BuChE-IN-2;FPS-ZM1;BChE-IN-8;4-(6-Bromo-2-benzothiazolyl)benzenamine;Timosaponin BII;Valiltramiprosate;Azeliragon;CRANAD-2
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