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SM1-71
CAS No. : 2088179-99-9
Biological Activity：SM1-71 (compound 5) is a potent TAK1 inhibitor, with a Ki of 160 nM, it also can covalently inhibit MKNK2, MAP2K1/2/3/4/6/7, GAK, AAK1, BMP2K, MAP3K7, MAPKAPK5, GSK3A/B, MAPK1/3, SRC, YES1, FGFR1, ZAK (MLTK), MAP3K1, LIMK1 and RSK2. SM1-71 can inhibit proliferation of multiple cancer cell lines[2][3].
Research Area：Cancer
Targets：MAP3K|Ribosomal S6 Kinase (RSK)|Src|FGFR|LIM Kinase (LIMK)
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;MAPK Compound Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Glutamine Metabolism Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Osteogenesis Compound Library;
Related Small Molecules:DB0614;KB SRC 4;Tirbanibulin dihydrochloride;Bafetinib;p60c-src substrate II;Caffeic acid-pYEEIE TFA;Ferulic acid-13C3;PP2;TAK1-IN-2;FGFR-IN-7;RSK2-IN-3;PP58;CRT0105950;FGFR3-IN-1;ENMD-2076 Tartrate;CH6953755;Eudesmin;R1530;RSK4-IN-1;FGFR3-IN-3;FMK-MEA;GSK-25;Fenlean;AT13148;Tyrosine kinase-IN-1;Heparan Sulfate
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