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Plerixafor-d4
CAS No. : 1246819-87-3
Biological Activity:Plerixafor-d4 is the deuterium labeled Plerixafor. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM[2][3][4][7].
Research Area:Cancer|Infection|Endocrinology|Inflammation/Immunology
Targets:CXCR|HIV
Related Small Molecules:Nicotinamide N-oxide;HIV-1 TAT (48-60);Seletracetam lithium;HIV-IN-2;Triptonine B;FC131;Peritassine A;CXCR4 antagonist 2;Flavopiridol;AMG 487 (S-enantiomer);TAT (48-57);FGI-106 tetrahydrochloride;(Z)-9-Propenyladenine;Apabetalone;CXCR4 antagonist 6;Decanoyl-RVKR-CMK TFA;ONX-0914 TFA;Apelin-36(rat, mouse);Ulonivirine
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