Sivelestat sodium tetrahydrate

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Sivelestat sodium tetrahydrate

CAS No. : 201677-61-4

Biological Activity：Sivelestat (EI546) sodium tetrahydrate is a competitive inhibitor of human neutrophil elastase, with an IC50 of 44 nM and a Ki of 200 nM. Sivelestat (EI546) sodium tetrahydrate has the potential for the study of acute lung injury/acute respiratory distress syndrome or disseminated intravascular coagulation in COVID-19[2][3][4].

Research Area：Cancer

Targets：Elastase|SARS-CoV

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Drug Repurposing Compound Library;FDA Approved & Pharmacopeial Drug Library;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Non-steroidal Anti-Inflammatory Compound Library;Coagulation and Anti-coagulation Compound Library;

Related Small Molecules:SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B;Proglumetacin;HCoV-229E-IN-1

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