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HL271
CAS No. : 1422365-52-3
Biological Activity：HL271 (IM156 hydrochloride; HL156A hydrochloride), a chemical derivative of Metformin (HY-B0627), is a potent AMPK activator that increases AMPK phosphorylation. HL271 attenuates aging-associated cognitive impairment in animal model[2]. HL271 is a potent oxidative phosphorylation (OXPHOS) inhibitor which can be used for the research of solid tumors[3].
Research Area：Cancer|Neurological Disease
Targets：AMPK
Related Small Molecules:AMPK activator 4;ZLN024;YLF-466D;BAY-3827;3α-Hydroxymogrol;HTH-01-015;TMPA;AICAR;Cimiracemoside C;EB-3D;COH-SR4;AMPK activator 7;Narazaciclib;D942;MARK4 inhibitor 1;Kazinol U;Phenformin hydrochloride;Karanjin;GSK621;Dorsomorphin;Palmitelaidic Acid;PF-06685249;Flufenamic acid-d4;PF-06679142
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