Palbociclib monohydrochloride

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Palbociclib monohydrochloride

CAS No. : 827022-32-2

Biological Activity:Palbociclib (PD 0332991) monohydrochloride is an orally active selective CDK4 and CDK6 inhibitor with IC50 values of 11 and 16 nM, respectively. Palbociclib monohydrochloride has potent anti-proliferative activity and induces cell cycle arrest in cancer cells, which can be used in the research of HR-positive and HER2-negative breast cancer and hepatocellular carcinoma[3][4].

Research Area:Cancer

Targets:CDK

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;CNS-Penetrant Compound Library;Peptidomimetic Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Chemical Probe Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Liver Cancer Compound Library ;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:DB0614;Dinaciclib;SNS-032;CC-671;(E/Z)-Zotiraciclib;CDK1-IN-4;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;GFB-12811;GSK 3 Inhibitor IX;Eciruciclib;CDK-IN-6;Lerociclib dihydrochloride;CDK4/6-IN-13;ON-013100;(2S,3R)-Voruciclib hydrochloride;Cucurbitacin E;THZ1;CDK2-IN-14-d3;CDK7-IN-2 hydrochloride hydrate;MeBIO;BSJ-4-116;Cirtuvivint

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