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Lomitapide mesylate
CAS No. : 202914-84-9
Biological Activity：Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.
IC50 value: 8 nM [1]
Target: MTP inhibitor
Lomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant to HMG-CoA reductase inhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain.
Research Area：Cardiovascular Disease
Targets：Microsomal Triglyceride Transfer Protein (MTP)
Related Small Molecules:CP-346086 dihydrate;Dirlotapide;PF-02575799;Implitapide;CP-319340(free base)
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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