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Tizoxanide

CAS No. : 173903-47-4

Biological Activity：Tizoxanide (TIZ) is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide (TIZ) has anti-HIV-1 activities and potent inhibition of both HBV and HCV replication with values EC₅₀ of 0.46μM and 0.15 μM, respectively. Tizoxanide also exerts anti-inflammatory effects by inhibiting the production of pro-inflammatory cytokines and suppressing of the activation of the NF-κB and the MAPK signaling pathways in LPS-treated macrophage cells^[3][4][5].

Research Area：Cancer|Infection

Targets：Parasite|Autophagy|Influenza Virus|HIV|Bacterial|IKK

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;NF-κB Signaling Compound Library;Stem Cell Signaling Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Antibacterial Compound Library;FDA Approved & Pharmacopeial Drug Library;Antiparasitic Compound library;Anti-Liver Cancer Compound Library ;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;

Related Small Molecules:(+)-Isopulegol;Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;HIV-1 TAT (48-60);Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Seletracetam lithium

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