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GSK2245035
CAS No. : 1207629-49-9
Biological Activity：GSK2245035 is a highly potent and selective intranasal Toll-Like receptor 7 (TLR7) agonist with preferential Type-1 interferon (IFN)-stimulating properties. GSK2245035 has pEC50s of 9.3 and 6.5 for IFNα and TFNα. GSK2245035 effectively suppresses allergen-induced Th2 cytokine production in human peripheral blood cell cultures. GSK2245035 is used for asthma.
Research Area：Inflammation/Immunology
Targets：IFNAR|TNF Receptor|Toll-like Receptor (TLR)
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Reprogramming Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Angiogenesis-Related Compound Library;
Related Small Molecules:C29;Akt/NF-κB/JNK-IN-1;AX-024;TMX-201;Cirsilineol;Ginsenoside F3;RS 09;ODN 20844;TLR7/8-IN-1;TLR8 agonist 5;QNZ;Sinulatumolin E;Deucravacitinib;Sulfo-ara-F-NMN;TLR7/8 antagonist 1;Gardiquimod;Epobis;PF-4878691;Tri(TLR4-IN-C34-PEG2-amide-PEG1)-amide-C3-COOH;Mulberroside A;Pepinh-TRIF TFA;Afimetoran;Sinulatumolin D;PDE4-IN-10;Ginsenoside Rc;Schaftoside
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