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Silychristin
CAS No. : 33889-69-9
Biological Activity:Silychristin is an abundant flavonolignan present in the fruits of Silybum marianum, with antioxidant properties. Silychristin is a potent inhibitor of the thyroid hormone transporter MCT8, and elicits a strong inhibition of T3 uptake with an IC50 of 110 nM[2].
Research Area:Endocrinology
Targets:Monocarboxylate Transporter
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Natural Product Library;Antioxidant Compound Library;Lipid Compound Library;Endocrinology Compound Library;Phenols Library;Traditional Chinese Medicine Active Compound Library;Flavonoids Library;Anti-Cancer Metabolism Compound Library;Food-Sourced Compound Library ;Plant-Sourced Natural Product Library;Human Metabolite Library;
Related Small Molecules:α-Cyano-4-hydroxycinnamic acid;AR-C141990 hydrochloride;MCT1-IN-2;MSC-4381;AR-C155858;7ACC2;AZD3965;BAY-8002;7ACC1;Syrosingopine;VB124
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