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AV-153 free base
CAS No. : 19350-66-4
Biological Activity：AV-153 free base, a 1,4-dihydropyridine (1,4-DHP) derivative, is an antimutagenic. AV-153 free base intercalates to DNA in a single strand break and reduces DNA damage, stimulates DNA repair in human cells in vitro. AV-153 free base interacts with thymine and cytosine and has an influence on poly(ADP)ribosylation. AV-153 free base has anti-cancer activity[2][3].
Research Area：Cancer
Targets：DNA/RNA Synthesis
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;
Related Small Molecules:Ametantrone;ddCTP trisodium;7-TFA-ap-7-Deaza-dA;P1788;Thymidine-13C5,15N;NSC 617145;116-9e;DNA Gyrase-IN-5;DMT-2′-F-Bz-dA;6-Thio-2′-Deoxyguanosine;Antitumor agent-74;Risdiplam;TH287 hydrochloride;Direct Black 38;7-TFA-ap-7-Deaza-ddA;BCH001;NKP-1339;Fialuridine;2′-O-MOE-5-Me-rC;PTC299;2′-F-Bz-dC Phosphoramidite
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