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Entrectinib
CAS No. : 1108743-60-7
Biological Activity：Entrectinib (NMS-E628) is a potent, orally available, and CNS-active pan-Trk, ROS1, and ALK inhibitor. Entrectinib inhibits TrkA, TrkB, TrkC, ROS1 and ALK with IC50 values of 1, 3, 5, 12 and 7 nM, respectively. Antitumor activity.
Research Area：Cancer
Targets：Autophagy|Trk Receptor|ROS Kinase|Anaplastic lymphoma kinase (ALK)
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Neuronal Signaling Compound Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Autophagy Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Targeted Therapy Drug Library ;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:ALK-IN-9;hTrkA-IN-1;IHMT-TRK-284;KRCA-0008;ANA-12;Alectinib-d8;Taletrectinib;Larotrectinib sulfate;N-Acetyl-5-hydroxytryptamine;MS4078;LM22B-10;TL13-22;D5261;NVP-TAE 684;N-Acetyl-5-hydroxytryptamine-d3;GGTI-2154 hydrochloride;MitoPQ;7,8-Dihydroxyflavone;TRK-IN-18;ALK5-IN-30;TL13-112;TRK-IN-12;ALK-IN-22;Alectinib;ALK-IN-12;CH7057288;ALK kinase inhibitor-1;Pan-Trk-IN-3
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