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CH-0793076 TFA
Biological Activity：CH-0793076 (TP3076) TFA, a hexacyclic camptothecin analog, is active drug and major metabolite of TP300. CH-0793076 TFA inhibits DNA topoisomerase I with an IC50 of 2.3 μM. CH-0793076 TFA is efficacious against cells expressing BCRP (breast cancer resistance protein).
Research Area：Cancer
Targets：Topoisomerase
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:Gepotidacin;Topoisomerase I/II inhibitor 3;(R)-Camptothecin-d5;Topoisomerase II inhibitor 8;FLT3-IN-13;TP3011;TAS-103 dihydrochloride;Rebeccamycin;AZD5099;TP0480066;Topoisomerase I inhibitor 4;Camptothecin;Corydamine;SW044248;9-Hydroxyellipticine hydrochloride;Flumequine-13C3;Trovafloxacin mesylate;Topoisomerase II inhibitor 12;Topoisomerase I inhibitor 3;Berberine sulfate;Betulinic acid;Hycanthone;Niranthin
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