For research use only. We do not sell to patients.
KB130015
CAS No. : 147030-48-6
Biological Activity：KB130015 (KB015) is an orally active and potent ThRα and ThRβ (Thyroid Hormone Receptor) inhibitor, with IC50 values of 4.5 and 5.1 μM, respectively. KB130015 has antiarrhythmic properties. KB130015 markedly slows the kinetics of inactivation of Na+ channels. KB130015 opens large-conductance Ca2+-activated K+ channels and relaxes vascular smooth muscle[2][3].
Research Area：Neurological Disease
Targets：Thyroid Hormone Receptor
Related Small Molecules:(D-Trp12,Tyr34)-pTH (7-34) amide (bovine);L-Thyroxine sodium;TR antagonist 1;TRβ agonist 1;1α-Hydroxy-3-epi-vitamin D3;DS08210767;Thyroxine sulfate;Thyroxine hydrochloride-13C6;Parathyroid Hormone (1-34), human, biotinylated;Parathyroid hormone (1-34) (rat);Tiratricol;NH-3;KAT681;Eprotirome;Resmetirom;Glutaurine;PCO371;Parathyroid Hormone (1-34), bovine;Sobetirome;DS69910557;Taltirelin acetate;T3-ATA (S-isomer);Reverse T3
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
- Structurally and synthetically diverse biologically active compounds；
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；
- Customized order volume ranging from milligrams to kilograms scale；
Structurally and synthetically diverse biologically active compounds；
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.
