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Navafenterol
CAS No. : 1435519-06-4
Biological Activity：Navafenterol (AZD-8871) is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile.
Research Area：Inflammation/Immunology
Targets：Adrenergic Receptor|mAChR
Related Small Molecules:VU0357017 hydrochloride;Todralazine;TBPB;ARC 239 dihydrochloride;Imidafenacin;Sabcomeline;Yohimbine;Glaucine;MK-6884;Salbutamol;Brompheniramine-d6 maleate;BI-167107;Talibegron hydrochloride;Arotinolol;SR59230A
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