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Fluorofenidone
CAS No. : 848353-85-5
Biological Activity：Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[2].
Research Area：Inflammation/Immunology
Targets：Akt|PI3K
Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Clinical Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Human Metabolite Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Cyclovirobuxine D;Rigosertib sodium;Tenalisib R Enantiomer;AKTide-2T;PI3kδ inhibitor 1;Sennidin A;PI3K/VEGFR2-IN-1;MS98;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;Artemisiane E;PI-103 Hydrochloride;IC-87114;PI3K/mTOR Inhibitor-6;Artemisinin-d3;PI3K-IN-10;SF2523;AS1949490;PI3K-IN-29;TD52 dihydrochloride;PI3K/mTOR Inhibitor-1;LM22B-10;PI3K-IN-26
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