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16-Hydroxycleroda-3,13-dien-15,16-olide
CAS No. : 141979-19-3
Biological Activity：16-Hydroxycleroda-3,13-dien-15,16-olide (16ξ-Hydroxycleroda-3,13-dien-15,16-olide; HCD), a clerodane diterpene, is a potent serine protease dipeptidyl peptidase 4 (DPP-4) inhibitor. 16-Hydroxycleroda-3,13-dien-15,16-olide down-regulates LPS-induced ERK phosphorylation in myocyte but blocks GLP-1 induced PKA expression. 16-Hydroxycleroda-3,13-dien-15,16-olide exhibits hypolipidemic, hepatoprotective, hypoglycemic efficacy.
Research Area：Metabolic Disease
Targets：Dipeptidyl Peptidase
Related Small Molecules:Cofrogliptin;Anagliptin-d6;P32/98;Talabostat;Dutogliptin;Gosogliptin;Prodipine hydrochloride;Diprotin B;Gemigliptin tartrate;Teneligliptin hydrobromide hydrate;Teneligliptin-d4;DBPR108;Anagliptin hydrochloride;UAMC00039 dihydrochloride;Retagliptin;Diprotin A TFA;Puromycin aminonucleoside
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