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CP681301

CAS No. : 865317-32-4

Biological Activity：CP681301 is a potent CDK5 inhibitor. CP681301 shows antiproliferative activity. CP681301 decreases the expression of CD133, OLIG2, SOX2, KI67, pCDK5 protein level in GSCs (Glioma stem cells). CP681301 reduces self-renewal in mouse glioma xenografts. CP681301 shows anti-tumor activity in Drosophila.

Research Area：Cancer

Targets：CDK

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:DB0614;Dinaciclib;SNS-032;CC-671;(E/Z)-Zotiraciclib;CDK1-IN-4;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;GFB-12811;GSK 3 Inhibitor IX;Eciruciclib;CDK-IN-6;Lerociclib dihydrochloride;CDK4/6-IN-13;ON-013100;(2S,3R)-Voruciclib hydrochloride;Cucurbitacin E;THZ1;CDK2-IN-14-d3;CDK7-IN-2 hydrochloride hydrate;MeBIO;BSJ-4-116;Cirtuvivint

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