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Purvalanol B
CAS No. : 212844-54-7
Biological Activity：Purvalanol B (NG 95) is a potent, selective, reversible and ATP-competitive inhibitor CDK, with IC50s of 6 nM, 6 nM, 9 nM, 6 nM for cdc2-cyclin B, CDK2-cyclin A, CDK2-cyclin E and CDK5-p35, respectively. Purvalanol B shows selectivity for CDK over a range of other protein kinases (IC50>1000 nM). Purvalanol B inhibits the growth a chloroquine-resistant strain of P. falciparum.
Research Area：Cancer|Infection
Targets：Parasite|CDK
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Antiparasitic Compound library;Cancer Stem Cells Compound Library;
Related Small Molecules:(+)-Isopulegol;DB0614;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;Dinaciclib;SNS-032;CC-671;(E/Z)-Zotiraciclib;SQ109;Trypanothione synthetase-IN-3;CDK1-IN-4;Pyrantel;CCT-251921;α-Terpinene;Dehydrocorydaline;BS-181;Samuraciclib hydrochloride hydrate;Niclosamide monohydrate;T025;Febrifugine dihydrochloride;Flavopiridol;CDK8-IN-3
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