Benzamil hydrochloride

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Benzamil hydrochloride

CAS No. : 161804-20-2

Biological Activity：Benzamil hydrochloride (Benzylamiloride hydrochloride), an Amiloride analogue, is a Na+/Ca2+ exchanger (NCX) inhibitor (IC50~100 nM). Benzamil hydrochloride also is a non-selective Deg/epithelial sodium channels (ENaC) blocker, and can potentiate myogenic vasoconstriction. Benzamil hydrochloride inhibits TRPP3-mediated Ca2+-activated currents, with an IC50 of 1.1 μM[2][3].

Research Area：Neurological Disease

Targets：Sodium Channel|Na+/Ca2+ Exchanger

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