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AChE/BuChE-IN-2

CAS No. : 1946008-31-6

Biological Activity：AChE/BuChE-IN-2 (Compound 5f) is an orally active AChE and BuChE inhibitor with IC₅₀ values of 0.72 μM and 0.16 μM, respectively. AChE/BuChE-IN-2 shows a non-competitive inhibition with AChE and shows potent self-induced β-amyloid (Aβ) aggregation inhibition with an IC₅₀ of 62.52 μM. AChE/BuChE-IN-2 can cross the BBB.

Research Area：Neurological Disease

Targets：Amyloid-β|Cholinesterase (ChE)

Related Small Molecules:β-Amyloid (13-27);Saikosaponin C;β-Amyloid (1-42), (rat/mouse) (TFA);Piperilate;β-Amyloid (12-28) (TFA);BuChE-IN-5;Ginsenoside Rg1;MDR-1339;AChE/BChE-IN-10;Timosaponin AIII;Trimyristin;AChE-IN-10;Isoimperatorin;Pseudocoptisine chloride;Itopride-d6 hydrochloride;β-Amyloid (11-22);Sinapine thiocyanate;sEH/AChE-IN-1;AChE-IN-11;20(S)-Ginsenoside Rg3;β-Amyloid (31-35);Heliosupine;(-)-Cyclopenin;Aβ-IN-1;Leptomerine

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