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Conoidin A
CAS No. : 18080-67-6
Biological Activity：Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII) with nematicidal properties. Conoidin A covalently binds to the peroxidatic Cys47 of TgPrxII, irreversibly inhibiting its hyperperoxidation activity with an IC50 of 23 µM. Conoidin A also inhibits hyperoxidation of mammalian PrxI and PrxII (but not PrxIII)[2]. Conoidin A has antioxidant, neuroprotective effects and can be used for the research of ischaemic heart disease[3].
Research Area：Infection|Neurological Disease|Cardiovascular Disease
Targets：Parasite
Related Screening Libraries:Bioactive Compound Library Plus;Anti-Infection Compound Library;Antioxidant Compound Library;Anti-Cardiovascular Disease Compound Library;Neuroprotective Compound Library;Antiparasitic Compound library;
Related Small Molecules:(+)-Isopulegol;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2;ML251
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