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GSK717
CAS No. : 1595278-21-9
Biological Activity：GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
Research Area：Inflammation/Immunology
Targets：NOD-like Receptor (NLR)
Related Screening Libraries:Bioactive Compound Library Plus;Immunology/Inflammation Compound Library; NF-κB Signaling Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Pyroptosis Compound Library;Targeted Diversity Library;Chemokine Compound Library;
Related Small Molecules:MCC950;Dapansutrile;NOD-IN-1;NLRP3-IN-4;NLRP3-IN-12;Nigericin;NLRP3-IN-5;β-Aminoarteether;NLRP3-IN-NBC6;Selnoflast;NOD1/2 antagonist-1;BMS-986299;NDT-30805;Licochalcone B;Emlenoflast sodium;AMS-17;NLRP3-IN-6;CY-09;NLRP3/AIM2-IN-1;Muscone;NLRP3-IN-8;INF4E;NLRP3-IN-2
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