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Safinamide-d4
CAS No. : 1147299-69-1
Biological Activity：Safinamide-d4 (FCE 26743-d4) is the deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM). Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8 µM) than at resting (IC50=262 µM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al[2][3].
Research Area：Neurological Disease
Targets：Monoamine Oxidase
Related Small Molecules:PXS-4728A;Hypericin;Simtuzumab;SSAO inhibitor-1;5-HT6R/MAO-B modulator 1;Glicoricone;MAO-B-IN-1;LOX-IN-3;LSD1-IN-16;β-Aminopropionitrile;Lazabemide;Monoamine oxidase/Aromatase-IN-1;PXS-5120A;Pirlindole mesylate;SSAO inhibitor-3;Ladostigil hemitartrate;MAO-B-IN-12;Pheniprazine;PF9601N
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