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Liarozole dihydrochloride
CAS No. : 1883548-96-6
Biological Activity：Liarozole (R75251) dihydrochloride is an imidazole derivative and orally active retinoic acid (RA) metabolism-blocking agent (RAMBA). Liarozole dihydrochloride inhibits the cytochrome P450 (CYP26)-dependent 4-hydroxylation of RA (IC50=7 μM), resulting in increased tissue levels of RA. Liarozole dihydrochloride shows antitumoral properties[2][3].
Research Area：Cancer|Metabolic Disease|Inflammation/Immunology
Targets：RAR/RXR|Cytochrome P450
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Orally Active Compound Library;Transcription Factor-Targeted Library;Rare Diseases Drug Library;Protein-protein Interaction Inhibitor Library;Human Metabolite Library;Nuclear Receptor Compound Library;
Related Small Molecules:SR9186;AMG-208;AGN 193109-d7;CYP1B1-IN-1;CYP2C9/CYP2C19-IN-1;Hypericin;Retinoic acid;Galeterone;Ranitidine;Bergapten;Ginsenoside Rd;AS1810722;Isoglycycoumarin;Polygalaxanthone III;Phenyltoloxamine;Ezutromid;Seviteronel;β-Apo-8′-carotenal;Diosmetin-d3;EDP-305;Fipronil
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